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Invitrogen™ CCDC36 Polyclonal Antibody
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Catalog No. PIPA5114403
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100 μg
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PIPA5114403 100 μg
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Catalog No. PIPA5114403 Supplier Invitrogen™ Supplier No. PA5114403
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue, human HL-60 whole cell. IHC: human testis cancer tissue, human melanoma tissue. ICC/IF: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC36
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene CCDC36
Gene Accession No. Q8IYA8
Gene Alias Cancer/testis antigen 74; Ccdc36; coiled-coil domain containing 36; coiled-coil domain-containing protein 36; CT74; IHO1; Interactor of HORMAD1 protein 1
Gene Symbols CCDC36
Host Species Rabbit
Immunogen E.coli-derived human CCDC36 recombinant protein (Position: E172-N472).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 339834
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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