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Invitrogen™ CCDC37 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528492

Catalog No. PIPA528492


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Description

Description

Recommended positive controls: HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CCDC37 (Coiled-Coil Domain-Containing 37) is a gene that encodes a protein involved in various cellular functions, including cytoskeletal organization, cell motility, and signal transduction. The gene is located on chromosome 9 and plays a crucial role in maintaining cell structure and function. Research has shown that CCDC37 is epigenetically repressed in certain cancers, such as lung tumors associated with chronic obstructive pulmonary disease (COPD). Methylation of the CCDC37 promoter is more prevalent in tumors from COPD patients, suggesting its role in tumor progression and possibly serving as a biomarker for cancer diagnosis and prognosis. Additionally, CCDC37 has been implicated in the regulation of ciliary function, further highlighting its importance in cellular processes. The protein's involvement in both cancer biology and ciliary dynamics underscores its multifaceted roles in health and disease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CCDC37
Polyclonal
Unconjugated
CFAP100
CCDC37; CFAP100; cilia and flagella associated protein 100; cilia- and flagella-associated protein 100; coiled-coil domain containing 37; coiled-coil domain-containing protein 37; MIA1
Rabbit
Antigen affinity chromatography
RUO
348807
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Q494V2
CFAP100
Recombinant protein encompassing a sequence within the N-terminus region of human CCDC37. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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