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Invitrogen™ CCDC37 Polyclonal Antibody
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Catalog No. PIPA561223
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100 μL
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PIPA561223 100 μL
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Catalog No. PIPA561223 Supplier Invitrogen™ Supplier No. PA561223
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PSANPFHLSG DVDFFLLRDQ ERNKALSERQ QQKTMRVHQK MTYSSKVSAK HTSLRRQLQL EDKQEDLEAR AEAEHQRAFR DYTTWKL Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 67%.

CCDC37 (Coiled-Coil Domain-Containing 37) is a gene that encodes a protein involved in various cellular functions, including cytoskeletal organization, cell motility, and signal transduction. The gene is located on chromosome 9 and plays a crucial role in maintaining cell structure and function. Research has shown that CCDC37 is epigenetically repressed in certain cancers, such as lung tumors associated with chronic obstructive pulmonary disease (COPD). Methylation of the CCDC37 promoter is more prevalent in tumors from COPD patients, suggesting its role in tumor progression and possibly serving as a biomarker for cancer diagnosis and prognosis. Additionally, CCDC37 has been implicated in the regulation of ciliary function, further highlighting its importance in cellular processes. The protein's involvement in both cancer biology and ciliary dynamics underscores its multifaceted roles in health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC37
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CFAP100
Gene Accession No. Q494V2
Gene Alias CCDC37; CFAP100; cilia and flagella associated protein 100; cilia- and flagella-associated protein 100; coiled-coil domain containing 37; coiled-coil domain-containing protein 37; MIA1
Gene Symbols CFAP100
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC37. Recombinant protein control fragment (Product #RP-100196).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 348807
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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