Invitrogen™ CCDC53 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558348

Catalog No. PIPA558348

Description

Immunogen sequence: LMGSGIDLTK VPAIQQKRTV AFLNQFVVHT VQFLNRFSTV CEEKLADLSL RIQQIETTLN ILDAKLSSIP GLDDVTVEVS P Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 95%.

Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt].

Specifications

• Antigen: CCDC53
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WASHC3
• Gene Alias: 2900091E11Rik; 5730495F03Rik; AD-016; Ccdc53; CGI-116; coiled-coil domain containing 53; coiled-coil domain-containing protein 53; RGD1563761; WASH complex subunit 3; WASH complex subunit CCDC53; WASHC3; x0009
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51019
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y3C0
• Gene Symbols: WASHC3
• Immunogen: Recombinant protein corresponding to Human CCDC53. Recombinant protein control fragment (Product #RP-97726).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG