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Invitrogen™ CCDC79 Polyclonal Antibody
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Catalog No. PIPA571009
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100 μL
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PIPA571009 100 μL
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Catalog No. PIPA571009 Supplier Invitrogen™ Supplier No. PA571009
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Human: 100%.

Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC79
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TERB1
Gene Accession No. Q8NA31
Gene Alias CCDC79; coiled-coil domain containing 79; coiled-coil domain-containing protein 79; telomere repeat binding bouquet formation protein 1; telomere repeats-binding bouquet formation protein 1; TERB1
Gene Symbols TERB1
Host Species Rabbit
Immunogen synthetic peptide directed towards the C-terminal region of human CCDC79.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283847
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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