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CCDC88A Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303101A

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Catalog No. 50-156-4257


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development; depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.
Specifications

Specifications

CCDC88A
Polyclonal
Unconjugated
CCDC88A
APE, GIRDIN, GIV, GRDN, HkRP1, KIAA1212; AKT-phosphorylation enhancer; Galpha-interacting vesicle-associated protein; G{alpha}-interacting vesicle-associated protein; Hook-related protein 1; akt phosphorylation enhancer; coiled-coil domain-containing protein 88A; g alpha-interacting vesicle-associated protein; girders of actin filament; girdin
Rabbit
Antigen affinity chromatography
RUO
55704
4° C
Liquid
Immunoprecipitation
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Q3V6T2
CCDC88A
Between 425 and 475
100 μL
Primary
Human
Antibody
IgG
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