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Invitrogen™ CCDC88C Polyclonal Antibody
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Catalog No. PIPA552215
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100 μL
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PIPA552215 100 μL
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Catalog No. PIPA552215 Supplier Invitrogen™ Supplier No. PA552215
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSLESSRNTS SNSSPLNLKG SSEQLHGRSE SFSSEDLIPS RDLATLPREA STPGRNALGR HEYPLPRNGP LPQEGAQKRG TAPPYVGVRP CSASPSSEMV TLEEFLEESN RSSPTHDTPS CRDDLLSD Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 79%.

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and is a negative regulator of the Wnt signaling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the disheveled protein. Disheveled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC88C
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CCDC88C
Gene Accession No. Q9P219
Gene Alias CCDC88C; coiled-coil domain containing 88C; Coiled-coil domain-containing protein 88C; DAPLE; Dvl-associating protein with a high frequency of leucine residues; hDaple; HkRP2; hook-related protein 2; KIAA1509; Protein Daple; SCA40; spinocerebellar ataxia 40
Gene Symbols CCDC88C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CCDC88C. Recombinant protein control fragment (Product #RP-89015).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 440193
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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