Invitrogen™ CCDC88C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144920

Catalog No. FEPA5144920

Description

Immunogen sequence: NGSVGKGPGD LKPKRGSPHR GSLDRTDAST DLAMRSWPSE LGSRTCSTSA TTTAPSNSTP IARHPGRTKG YNSDDNLCEP SLE Antigen sequence identity: Mouse 78%; Rat 76%.

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and is a negative regulator of the Wnt signaling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the disheveled protein. Disheveled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain.

Specifications

• Antigen: CCDC88C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCDC88C
• Gene Alias: CCDC88C; coiled-coil domain containing 88C; Coiled-coil domain-containing protein 88C; DAPLE; Dvl-associating protein with a high frequency of leucine residues; hDaple; HkRP2; hook-related protein 2; KIAA1509; Protein Daple; SCA40; spinocerebellar ataxia 40
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 440193
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry, Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9P219
• Gene Symbols: CCDC88C
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1475-1557. Recombinant protein control fragment (Product #a href=.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid