CCDC88C Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 257691AP150UL

Catalog No. 50-173-5066

Description

This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the disheveled protein and is a negative regulator of the Wnt signaling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the disheveled protein. Disheveled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintece, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain.

Specifications

• Antigen: CCDC88C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCDC88C
• Gene Alias: CCDC88C, DAPLE, hDaple, HkRP2, Hook related protein 2, KIAA1509, Protein Daple
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 440193
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9P219
• Gene Symbols: CCDC88C
• Immunogen: CCDC88C Fusion Protein Ag22711
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG