Invitrogen™ CCDC94 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531689

Catalog No. PIPA531689

Description

Recommended positive controls: Jurkat. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt].

Specifications

• Antigen: CCDC94
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCDC94
• Gene Alias: 2900016D05Rik; AI413813; Ccdc94; coiled-coil domain containing 94; coiled-coil domain-containing protein 94; Splicing factor YJU2; YJU2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55702
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.69 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9BW85
• Gene Symbols: CCDC94
• Immunogen: Recombinant fragment corresponding to a region within amino acids 103 and 323 of Human CCDC94.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG