Invitrogen™ CCL16 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Supplier:  Invitrogen™ 500P125GBT500UG

Catalog No. 50-271-8688

Description

AA Sequence of recombinant protein: QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human LEC (CCL16). Anti-Human LEC (CCL16)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human LEC (CCL16) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human LEC (CCL16) (500-P125G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human LEC (CCL16). Western Blot: To detect hLEC by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hLEC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P125GBT-1MG will be provided as 2 x 500 μg

CCL16 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL16 displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10.

Specifications

• Antigen: CCL16
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: CCL16
• Gene Alias: C-C motif chemokine 16; C-C motif chemokine ligand 16; CCL16; chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; CKb12; HCC-4; IL-10-inducible chemokine; ILINCK; LCC-1; LEC; liver CC chemokine-1; liver-expressed chemokine; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; monotactin-1; MTN-1; NCC4; NCC-4; new CC chemokine 4; SCYA16; SCYL4; small inducible cytokine subfamily A (Cys-Cys), member 16; small-inducible cytokine A16
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6360
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O15467
• Gene Symbols: CCL16
• Immunogen: E.coli-derived Recombinant Human LEC (CCL16).
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG