Invitrogen™ CCL23 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547528

Catalog No. PIPA547528

Description

In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) MIP-1 gamma and rhHCC-1 is observed and 5% cross-reactivity with recombinant mouse MIP-1 gamma is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: CCL23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCL23
• Gene Alias: C6 beta-chemokine; C-C motif chemokine 23; C-C motif chemokine ligand 23; CCL23; CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99); chemokine (C-C motif) ligand 23; Ck beta 8-1; CKb8; CKB-8; Ckb-8-1; CK-BETA-8; hmrp-2a; Macrophage inflammatory protein 3; MIP3; MIP-3; MIP-3CK-BETA-8; MPIF1; MPIF-1; MPIF-1Ckb-8-1; Myeloid progenitor inhibitory factor 1; SCYA23; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6368
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P55773
• Gene Symbols: CCL23
• Immunogen: E. coli-derived recombinant human CCL23/MPIF-1 Arg22-Asn120.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov