Invitrogen™ CCL23 Recombinant Rabbit Monoclonal Antibody (004)

Catalog No.	Quantity
PIMA530152	100 μL

Catalog No. PIMA530152 Supplier Invitrogen™ Supplier No. MA530152

Description

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human CCL23/MIP 3.

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: CCL23
• Applications: ELISA
• Classification: Recombinant Monoclonal
• Clone: 004
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: CCL23
• Gene Accession No.: P55773
• Gene Alias: C6 beta-chemokine; C-C motif chemokine 23; C-C motif chemokine ligand 23; CCL23; CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99); chemokine (C-C motif) ligand 23; Ck beta 8-1; CKb8; CKB-8; Ckb-8-1; CK-BETA-8; hmrp-2a; Macrophage inflammatory protein 3; MIP3; MIP-3; MIP-3CK-BETA-8; MPIF1; MPIF-1; MPIF-1Ckb-8-1; Myeloid progenitor inhibitory factor 1; SCYA23; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23
• Gene Symbols: CCL23
• Host Species: Rabbit
• Immunogen: Recombinant Human CCL23/MIP 3 Protein (Arg22-Asn120).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6368
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG