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CCL3 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

$250.00 - $2175.00

Specifications

Antigen CCL3
Concentration 0.1-1.0 mg/mL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
500P12150UG
Encompass_Preferred
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Invitrogen™
500P12150UG
50 μg
Each for $250.00
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500P121100
Encompass_Preferred
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Invitrogen™
500P121100UG
100 μg
Each for $319.00
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500P1211MG
Encompass_Preferred
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Invitrogen™
500P1211MG
1 mg
Each for $2,175.00
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Description

Description

AA Sequence of recombinant protein: APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine MIP-1alpha (CCL3). Anti-Murine MIP-1alpha (CCL3)-specific antibody was purified by affinity chromatography employing an immobilized Murine MIP-1alpha (CCL3) matrix. Sandwich ELISA: To detect Murine MIP-1alpha (CCL3) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine MIP-1alpha (CCL3) (500-P121Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine MIP-1alpha (CCL3). Western Blot: To detect Murine MIP-1alpha (CCL3) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine MIP-1alpha (CCL3) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
Specifications

Specifications

CCL3
ELISA, Western Blot
Unconjugated
Rabbit
Mouse
P10855
20302
E.coli-derived Recombinant Murine MIP-1alpha (CCL3).
Antigen affinity chromatography
Ccl3
0.1-1.0 mg/mL
Polyclonal
Lyophilized
RUO
PBS with no preservative
AI323804; C-C motif chemokine 3; C-C motif chemokine ligand 3; CCL3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; G0S19-1; Heparin-binding chemotaxis protein; H-MIP-1-alpha; L2G25B; LD78ALPHA; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3); macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; MIP1 (a); mip1 alpha; MIP-1 alpha; MIP1-(a); MIP1A; MIP-1a; MIP-1alpha; MIP-1-alpha; MIP1-alpha; MIP-1-alpha(4-69); PAT 464.1; RP23-320E6.7; Scya3; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5
Ccl3
Primary
-20°C
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