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CCL5 (RANTES) Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
$250.00 - $2175.00
Specifications
Antigen | CCL5 (RANTES) |
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Concentration | 0.1-1.0 mg/mL |
Applications | ELISA, Western Blot |
Classification | Polyclonal |
Conjugate | Biotin |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
500P78BT25
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Invitrogen™
500P78BT25UG |
25 μg |
Each for $250.00
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500P78BT50
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Invitrogen™
500P78BT50UG |
50 μg |
Each for $319.00
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50-271-8449
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Invitrogen™
500P78BT500UG |
500 μg |
Each for $2,175.00
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Description
AA Sequence of recombinant protein: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat RANTES (CCL5). Anti-Rat RANTES (CCL5)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Rat RANTES by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Rat RANTES (500-P78) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat RANTES. Western Blot: To detect Rat RANTES by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Rat RANTES is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P78BT-1MG will be provided as 2 x 500 μg
CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.Specifications
CCL5 (RANTES) | |
ELISA, Western Blot | |
Biotin | |
Rabbit | |
Rat | |
P50231 | |
81780 | |
E.coli-derived, 7.9 kDa Recombinant Rat RANTES (CCL5). | |
Antigen Affinity Chromatography | |
CCL5 |
0.1-1.0 mg/mL | |
Polyclonal | |
Lyophilized | |
RUO | |
PBS with no preservative | |
beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014) | |
CCL5 | |
Primary | |
-20°C |
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