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CCM2 Monoclonal Antibody (OTI3B7), TrueMAB™, OriGene

Mouse Monoclonal Antibody
Supplier: OriGene TA503397

Description
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.Specifications
CCM2 | |
Monoclonal | |
0.24 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q9BSQ5 | |
CCM2 | |
Full length human recombit protein of human CCM2 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI3B7 | |
Unconjugated | |
CCM2 | |
C7orf22, OSM, PP10187 | |
Mouse | |
Affinity Chromatography | |
RUO | |
83605 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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