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Invitrogen™ CCM2 Polyclonal Antibody

Goat Polyclonal Antibody
Supplier: Invitrogen™ PA518604
Description
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
CCM2 | |
Polyclonal | |
Unconjugated | |
CCM2 | |
BC029157; C7orf22; Ccm2; CCM2 scaffolding protein; cerebral cavernous malformation 2; cerebral cavernous malformation 2 homolog; cerebral cavernous malformations 2 protein; Cerebral cavernous malformations protein 2 homolog; malcavernin; MGC4067; MGC4607; MGC74868; Oncostatin; OncostatinM; Osm; osmosensing scaffold for MEKK3; PP10187 | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
305505, 83605 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Flow Cytometry, Western Blot, Immunocytochemistry | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
Q9BSQ5 | |
CCM2 | |
Synthetic peptide sequence (KGEKSRDKKAHEK) corresponding to the internal amino acids of CCM2 (aa 23-36). | |
100 μg | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
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