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CCM3/PDCD10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501726185 Shop All Proteintech Group Inc Products
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Catalog No. 50-172-6185 Supplier Proteintech Group Inc Supplier No. 102942AP150UL
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Rabbit Polyclonal Antibody

10294-2-AP is a rabbit polyclonal antibody raised against the full-length PDCD10 of human origin.

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

Antigen CCM3/PDCD10
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene PDCD10
Gene Accession No. Q6NX65, Q8VE70, Q9BUL8
Gene Alias CCM3, PDCD10, programmed cell death 10, TFAR15
Gene Symbols Pdcd10
Host Species Rabbit
Immunogen CCM3/PDCD10 Fusion Protein Ag0348
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11235, 494345, 56426
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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