CCM3/PDCD10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 102942AP150UL

Catalog No. 50-172-6185

Description

10294-2-AP is a rabbit polyclonal antibody raised against the full-length PDCD10 of human origin.

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: CCM3/PDCD10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDCD10
• Gene Alias: CCM3, PDCD10, programmed cell death 10, TFAR15
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11235, 494345, 56426
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q6NX65, Q8VE70, Q9BUL8
• Gene Symbols: Pdcd10
• Immunogen: CCM3/PDCD10 Fusion Protein Ag0348
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG