Invitrogen™ CCP110 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103725

Catalog No. PIPA5103725

Description

Antibody detects endogenous levels of total CEP110.

Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt].

Specifications

• Antigen: CCP110
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCP110
• Gene Alias: 6330503K22Rik; AA415922; AI427129; AW557948; CCP110; centriolar coiled coil protein 110; centriolar coiled coil protein 110kDa; centriolar coiled-coil protein 110; centriolar coiled-coil protein 110kDa; centriolar coiled-coil protein of 110 kDa; Centriolin; centrosomal protein CP110; centrosomal protein of 110 kDa; CEP1; Cep110; CNTRL; CP110; FAN; Kiaa0419; RGD1310509
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101565, 361634, 9738
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O43303, Q7TSH4
• Gene Symbols: CCP110
• Immunogen: A synthesized peptide derived from human CCP110(Accession O43303), corresponding to amino acid residues A866-Q916.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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