CCR1 Mouse anti-Human, Clone:8E10G6, Abnova™
Mouse monoclonal antibody raised against recombinant human CCR1.
Manufacturer: Abnova Corporation MAB17627
DescriptionThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq]
|chemokine (C-C motif) receptor 1|
|In PBS (0.05% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|ELISA, Flow Cytometry, Western Blot|
Western Blot (1:500-1:2000)
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
|CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1|
|Recombinant protein corresponding to amino acid of human CCR1 from E. coli.|
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