CCR1 Mouse anti-Human, Clone:8E10G6, Abnova™

Catalog No.	Quantity
89-333-966	100 μg

Catalog No. 89-333-966 Supplier Abnova Corporation Supplier No. MAB17627

Description

Mouse monoclonal antibody raised against recombinant human CCR1.

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq]

Specifications

• Antigen: CCR1
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 8E10G6
• Conjugate: Unconjugated
• Description: chemokine (C-C motif) receptor 1
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: CCR1
• Gene Alias: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid of human CCR1 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 1230
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1