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Invitrogen™ CCR1 Recombinant Rabbit Monoclonal Antibody (003), Invitrogen™
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Catalog No. PIMA543067
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PIMA543067 100 μL
PIMA543466 50 μL
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Catalog No. PIMA543067 Supplier Invitrogen™ Supplier No. MA543067
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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Human CCR1

Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR1
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone 003
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CCR1
Gene Accession No. P32246
Gene Alias C-C chemokine receptor type 1; C-C CKR-1; C-C motif chemokine receptor 1; CC-CKR-1; Ccr1; CCR-1; CD191; chemokine (C-C motif) receptor 1; chemokine (C-C) receptor 1; CKR1; CKR-1; CMKBR1; CMKR1; HM145; LD78 receptor; macrophage inflammatory protein 1-alpha receptor; macrophage inflammatory protein-1 alpha receptor; MIP-1 alpha R; MIP-1 alphaR; MIP-1alpha-R; MIP1aR; Mip-1a-R; RANTES receptor; RANTES-R; SCYAR1
Gene Symbols CCR1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the center region of the Human CCR1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1230
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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