Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA547847

Invitrogen™ CCR3 Chimeric Recombinant Rabbit Monoclonal Antibody (5E8-G9-B4)
GREENER_CHOICE

Catalog No. PIMA547847
Change view
Click to view available options
Quantity:
200 μg
Catalog No. Quantity
PIMA547847 200 μg
1 options

Catalog No. PIMA547847

Supplier: Invitrogen™ MA547847

Only null left
Add to Cart
Add to Cart

Description

Rabbit Recombinant Monoclonal Antibody

Specificity: Recognises human CCR3, a chemokine receptor highly expressed of eosinophils, as well as Th2-Tcells, basophils, platelets, mast-cells, mononuclear phagocytes, airway epithelial cells, and hematopoietic progenitor cells (CD34+).

CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR3 Chimeric
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 5E8-G9-B4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene CCR3
Gene Accession No. P51677
Gene Alias b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3
Gene Symbols CCR3
Host Species Rabbit
Immunogen Proprietary sequence.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1232
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.