CCR3 Mouse anti-Human, Clone:8E9H10, Abnova™

Mouse monoclonal antibody raised against recombinant human CCR3.

Supplier:  Abnova Corporation MAB17962

Catalog No. 89-334-315

Description

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq]

Specifications

• Antigen: CCR3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Western Blot (1:100-1:500)
  The optimal working dilution should be determined by the end user.
• Gene: CCR3
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 8E9H10
• Description: chemokine (C-C motif) receptor 3
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
• Immunogen: Recombinant protein corresponding to human CCR3.
• Gene ID (Entrez): 1232
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid