CCR3 Mouse anti-Human, Clone:8E9H10, Abnova™

Catalog No.	Quantity
89-334-015	100 μg

Catalog No. 89-334-015 Supplier Abnova Corporation Supplier No. MAB17591

Description

Mouse monoclonal antibody raised against recombinant human CCR3.

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq]

Specifications

• Antigen: CCR3
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 8E9H10
• Conjugate: Unconjugated
• Description: chemokine (C-C motif) receptor 3
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: CCR3
• Gene Alias: CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid of human CCR3 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 1232
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1