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Invitrogen™ CCR3 Polyclonal Antibody
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Catalog No. 01675508
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100 μg
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Catalog No. Quantity
01-675-508 100 μg
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Catalog No. 01-675-508 Supplier Invitrogen™ Supplier No. PA141377
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Description

Rabbit Polyclonal Antibody

Suggested positive control: antigen standard for CCR3 (transient overexpression lysate), Daudi.

CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta. CCR3 trasnduces a signal by increasing the intracellular calcium ions level. It also serves as an alternative co-receptor with CD4 for HIV-1 infection. Other chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CCR3
Gene Accession No. O54814, P51677, P51678
Gene Alias b-chemokine receptor; CC chemokine receptor 3; C-C chemokine receptor type 3; C-C CKR-3; C-C motif chemokine receptor 3; CC-CKR3; CC-CKR-3; Ccr3; CCR-3; CD193; chemokine (C-C motif) receptor 3; chemokine (C-C) receptor 1,-like 2; chemokine (C-C) receptor 3; CKR3; Cmkbr1l2; CMKBR3; eosinophil CC chemokine receptor 3; eosinophil eotaxin receptor; Macrophage inflammatory protein 1-alpha receptor-like 2; MGC102841; MIP-1 alpha RL2; MIP-1 alphaRL2; probable C-C chemokine receptor type 3
Gene Symbols CCR3
Host Species Rabbit
Immunogen Synthetic peptide of human CCR3 protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117027, 1232, 12771
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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