CCR5 Mouse anti-Human, Clone: T21/8, Abnova™

Catalog No.	Quantity
89-933-735	50 μg

Catalog No. 89-933-735 Supplier Abnova Corporation Supplier No. MAB12618

Description

Mouse monoclonal antibody raised against human CCR5.

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: CCR5
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: T21/8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human CCR5.
• Dilution: ELISA Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
• Formulation: In aqueous buffer (Stabilizer, 0.09% sodium azide).
• Gene Alias: CC-CKR-5/CCCKR5/CD195/CKR-5/CKR5/CMKBR5/IDDM22
• Gene Symbols: CCR5
• Host Species: Mouse
• Immunogen: Human CCR5
• Purification Method: Affinity purification
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1234
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ