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Invitrogen™ CCR8 Polyclonal Antibody

Catalog No. PIPA129909
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50 μg
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Catalog No. Quantity
PIPA129909 50 μg
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Catalog No. PIPA129909 Supplier Invitrogen™ Supplier No. PA129909

Description

Goat Polyclonal Antibody

Recommended positive controls: Human K562 cells (ICC)and human spleen (IHC-P). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR8
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 0.14M NaCl and 0.1% sodium azide
Gene CCR8
Gene Accession No. P51685, P56484
Gene Alias C-C; CC chemokine receptor 8; CC chemokine receptor CHEMR1; C-C chemokine receptor type 8; C-C CKR-8; C-C motif chemokine receptor 8; CC-chemokine receptor chemr1; CC-CKR-8; CCR8; CCR-8; cd198; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; chemokine receptor-like 1; CKR-8; CKRL1; CKR-L1; Cmkbr8; CMKBRL2; CY6; GPRCY6; GPR-CY6; mCCR8; MGC129966; MGC129973; TER1
Gene Symbols CCR8
Host Species Goat
Immunogen Synthetic peptide C-183-YSFYNQQTLK-193 corresponding to the 2nd extracellular domain sequence of human CCR8.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1237, 12776
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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