Invitrogen™ CCRL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540819

Catalog No. PIPA540819

Description

Peptide sequence: LSAQLVPSLC SAVFVIGVLD NLLVVLILVK YKGLKRVENI YLLNLAVSNL Sequence homology: Cow: 77%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 90%; Rat: 82%.

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immunal tissues (predominanly spleen, fetal liver, bone marrow and lymph node). It shares over 40% homology with other C-C chemokine receptors but does not share the conserved DRY motif which is among the important motifs necessary for signalling and ligand-binding. C-C chemokine receptors are G-protein coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation.

Specifications

• Antigen: CCRL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCRL2
• Gene Alias: 1810047I05Rik; Ackr5; atypical chemokine receptor 5; C-C chemokine receptor-like 2; C-C motif chemokine receptor like 2; CCR11; CCR6; Ccrl2; chemokine (C-C motif) receptor-like 2; chemokine C-C motif receptor-like 2; chemokine C-C motif receptor-like 2-like; chemokine receptor CCR11; Chemokine receptor X; CKRX; Cmkbr1l2; CRAM; CRAM-A; CRAM-B; E01; G-protein coupled beta chemokine receptor; HCR; Lccr; L-CCR; Lipopolysaccharide-inducible C-C chemokine receptor; LOC100719164; MGC116710; Putative MCP-1 chemokine receptor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9034
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O00421
• Gene Symbols: CCRL2
• Immunogen: Synthetic peptide directed towards the N-terminal of human CCRL2 (aa 36-85).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG