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CCT 018159, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
171009-07-7
C20H20N2O4
352.39
BBTMGPQSLSYPHE-UHFFFAOYSA-N
6-4-2,3-dihydro-1,4-benzodioxin-6-yl-5-methyl-1,2-dihydropyrazol-3-ylidene-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one,kinome_3591,owpmenvyxdjdow-uhfffaoysa-n,4-4-2,3-dihydro-benzo 1,4 dioxin-6-yl-5-methyl-1h-pyrazol-3-yl-6-ethyl-benzene-1,3-diol
6749166
6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one
CCC1=CC(=C2C(=C(NN2)C)C3=CC4=C(C=C3)OCCO4)C(=O)C=C1O
This item is not returnable. View return policy
171009-07-7
C20H20N2O4
352.39
BBTMGPQSLSYPHE-UHFFFAOYSA-N
6-4-2,3-dihydro-1,4-benzodioxin-6-yl-5-methyl-1,2-dihydropyrazol-3-ylidene-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one,kinome_3591,owpmenvyxdjdow-uhfffaoysa-n,4-4-2,3-dihydro-benzo 1,4 dioxin-6-yl-5-methyl-1h-pyrazol-3-yl-6-ethyl-benzene-1,3-diol
6749166
6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one
CCC1=CC(=C2C(=C(NN2)C)C3=CC4=C(C=C3)OCCO4)C(=O)C=C1O

Hsp90 inhibitor

Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC 50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression.

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Quantity 10mg
Formula Weight 352.39
Percent Purity >98%
Chemical Name or Material CCT 018159

Recommended Storage : Store at +4°C