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CCT 018159, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression.
Specifications
Quantity | 50 mg |
Formula Weight | 352.39 |
Percent Purity | >98% |
Chemical Name or Material | CCT 018159 |
Safety and Handling
Recommended Storage | Store at +4°C |
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