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Tocris Bioscience™ CCT 018159
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Catalog No. 243550
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Catalog No. Quantity
24-355-0 50 mg
24-351-0 10 mg
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Catalog No. 24-355-0 Supplier Tocris Bioscience™ Supplier No. 2435/50
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Description

Hsp90 inhibitor

Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression.

Chemical Identifiers

CAS 171009-07-7
Molecular Formula C20H20N2O4

Specifications

Quantity 50 mg
Formula Weight 352.39
Purity >98%
Molecular Weight (g/mol) 352.39
Chemical Name or Material CCT 018159

Safety and Handling

Recommended Storage Store at +4°C
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