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CD100 Monoclonal Antibody (A8), APC, Invitrogen™

Catalog No. PIMA516558
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100 Tests
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Catalog No. Quantity
PIMA516558 100 Tests
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Catalog No. PIMA516558 Supplier Thermo Scientific Supplier No. MA516558

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4oC in the dark. Once reconstituted, this product has a shelf life of approx. 18 months. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD100
Applications Flow Cytometry
Classification Monoclonal
Clone A8
Concentration Conc. Not Determined
Conjugate APC
Formulation PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Sema4d
Gene Accession No. Q92854
Gene Alias A8; BB18; C9orf164; CD100; coll-4; GR3; M-Sema G; M-sema-G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; sema J; Sema4d; Semacl2; SEMAJ; semaphorin 4D; semaphorin H; semaphorin-4D; Semaphorin-C-like 2; semaphorin-J; Semcl2
Gene Symbols Sema4d
Host Species Mouse
Immunogen Human PHA activated lymphocytes
Purification Method Protein G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10507
Target Species Human, Non-human Primate
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Lyophilized
Isotype IgG1
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