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Invitrogen™ CD100 (SEMA4D) Monoclonal Antibody (M188)
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Catalog No. PIMA547680
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100 μL
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PIMA547680 100 μL
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Catalog No. PIMA547680 Supplier Invitrogen™ Supplier No. MA547680
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Description

Mouse Monoclonal Antibody

This antibody detects a 150 kDa* band on SDS-PAGE immunoblots of adult mouse brain.

Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD100 (SEMA4D)
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone M188
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Sema4d
Gene Accession No. O09126, Q92854
Gene Alias A8; BB18; C9orf164; CD100; coll-4; GR3; M-Sema G; M-sema-G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; sema J; Sema4d; Semacl2; SEMAJ; semaphorin 4D; semaphorin H; semaphorin-4D; Semaphorin-C-like 2; semaphorin-J; Semcl2
Gene Symbols Sema4d
Host Species Mouse
Immunogen Clone (M188) was generated from a recombinant protein corresponding to the C-terminal region of human Semaphorin-4D.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10507, 20354, 306790
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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