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CD101 Mouse anti-Human, PE, Clone: V7.1, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 566371
Description
The V7.1 monoclonal antibody specifically recognizes CD101 which is also known as P126 or Glu-Trp-Ile EWI motif-containing protein 101 (EWI-101). CD101 is encoded by IGSF2 (Immunoglobulin superfamily member 2) and belongs to the EWI (sharing a conserved glutamine-tryptophan-isoleucine motif) family within the Ig superfamily. CD101 is a ñ135-140 kDa type I transmembrane glycoprotein that has a short cytoplasmic domain with potential phosphorylation sites and an extracellular region with seven immunoglobulin-variable (IgV)-like domains. CD101 is expressed as homodimers by granulocytes, monocytes, dendritic cells, and some T cells. Its expression by T cells may be upregulated upon activation through the CD3 complex. CD101 may play a role in TCR/CD3-dependent T-cell activation.
R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.Specifications
CD101 | |
V7.1 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
Monoclonal | |
PE | |
IGSF2, Cell surface glycoprotein V7, V7, EWI-101, P126 | |
T cell clone CS1 | |
100 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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