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CD102 Mouse, anti-Mouse, R718, Clone: 3C4(MIC2/4), BD OptiBuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 752096

Catalog No. BDB752096


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Description

Description

The 3C4 (mIC2/4) monoclonal antibody specifically binds to the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD102
Monoclonal
R718
50 μg
Primary
Refrigerate Upon Arrival
Flow Cytometry
3C4(MIC2/4)
Mouse
RUO
Mouse
Liquid
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