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Invitrogen™ CD103 Monoclonal Antibody (OX-62), FITC

Mouse Monoclonal Antibody

$323.50 - $660.50

Specifications

Antigen CD103
Clone OX-62
Concentration 0.1 mg/mL
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Applications Flow Cytometry
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIMA517569
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Invitrogen™
MA517569
100 μg
Each for $323.50
Only null left
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PIMA517570
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Invitrogen™
MA517570
500 μg
Each for $660.50
Only null left
Add to Cart
 
Description

Description

CD103 Monoclonal Antibody for Flow

CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.
Specifications

Specifications

CD103
0.1 mg/mL
Flow Cytometry
FITC
Mouse
RUO
PBS with 4-5mg/mL BSA and 0.02% sodium azide
0
83577
Rat PVG density gradient-enriched veiled cells (obtained from the cannulated thoracic duct of mesenteric lymphadenectomized rats) were fused with NSO myeloma cells.
Antibody
OX-62
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Monoclonal
Liquid
IgG1
Rat
Itgae
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen
Itgae
Primary
Protein G
Videos
SDS
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Documents

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