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Invitrogen™ CD103 Monoclonal Antibody (OX-62), FITC
Mouse Monoclonal Antibody
$323.50 - $660.50
Specifications
Antigen | CD103 |
---|---|
Clone | OX-62 |
Concentration | 0.1 mg/mL |
Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
Applications | Flow Cytometry |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIMA517569
|
Invitrogen™
MA517569 |
100 μg |
Each for $323.50
|
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PIMA517570
|
Invitrogen™
MA517570 |
500 μg |
Each for $660.50
|
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Description
CD103 Monoclonal Antibody for Flow
CD103 (ITGAE, Integrin alpha E) is molecule that is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. In particular, CD103 includes a 150kDa alpha chain and a 120kDa beta chain. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is part of the integrin family which are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, CD103 protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. CD103 is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. Diseases associated with CD103 dysfunction include hairy cell leukemia and splenic marginal zone lymphoma.Specifications
CD103 | |
0.1 mg/mL | |
Flow Cytometry | |
FITC | |
Mouse | |
RUO | |
PBS with 4-5mg/mL BSA and 0.02% sodium azide | |
0 | |
83577 | |
Rat PVG density gradient-enriched veiled cells (obtained from the cannulated thoracic duct of mesenteric lymphadenectomized rats) were fused with NSO myeloma cells. | |
Antibody |
OX-62 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. | |
Monoclonal | |
Liquid | |
IgG1 | |
Rat | |
Itgae | |
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen | |
Itgae | |
Primary | |
Protein G |
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