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Invitrogen™ CD104 Monoclonal Antibody (10B10D5)
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Catalog No. PIMA517104
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100 μg
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Catalog No. Quantity
PIMA517104 100 μg
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Catalog No. PIMA517104 Supplier Invitrogen™ Supplier No. MA517104
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Description

Mouse Monoclonal Antibody

MA5-17104 targets ITGB4 in FACS, IHC and WB applications and shows reactivity with Human samples. The MA5-17104 immunogen is purified recombinant fragment of human ITGB4 (amino acids: 1619-1822) expressed in E. Coli. MA5-17104 detects ITGB4 which has a predicted molecular weight of approximately 202kDa.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD104
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 10B10D5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene ITGB4
Gene Accession No. P16144
Gene Alias AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4
Gene Symbols ITGB4
Host Species Mouse
Immunogen Purified recombinant fragment of human ITGB4 (amino acids: 1619-1822) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3691
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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