Invitrogen™ CD104 Monoclonal Antibody (422325), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523535

Catalog No. PIMA523535

Description

In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 5, beta 6, beta 8, or recombinant mouse Integrin beta 4 is observed.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: CD104
• Classification: Monoclonal
• Conjugate: APC
• Gene: ITGB4
• Gene Alias: AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 3691
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: 422325
• Formulation: Buffered saline solution with BSA and 0.09% sodium azide
• Gene Accession No.: P16144
• Gene Symbols: ITGB4
• Immunogen: CHO-derived recombinant human Integrin beta 4/CD104 Asn28-Ser710.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b