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Invitrogen™ CD104 Monoclonal Antibody (422325), APC
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Catalog No. PIMA523535
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100 Tests
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Catalog No. Quantity
PIMA523535 100 Tests
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Catalog No. PIMA523535 Supplier Invitrogen™ Supplier No. MA523535
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Description

Mouse Monoclonal Antibody

In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 5, beta 6, beta 8, or recombinant mouse Integrin beta 4 is observed.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD104
Applications Flow Cytometry
Classification Monoclonal
Clone 422325
Conjugate APC
Formulation Buffered saline solution with BSA and 0.09% sodium azide
Gene ITGB4
Gene Accession No. P16144
Gene Alias AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4
Gene Symbols ITGB4
Host Species Mouse
Immunogen CHO-derived recombinant human Integrin beta 4/CD104 Asn28-Ser710.
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3691
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2b
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