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Invitrogen™ CD105 (Endoglin) Polyclonal Antibody
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Catalog No. PIPA579203
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100 μg
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Catalog No. Quantity
PIPA579203 100 μg
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Catalog No. PIPA579203 Supplier Invitrogen™ Supplier No. PA579203
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: mouse lung tissue. IHC: mouse kidney tissue, mouse liver tissue, mouse spleen tissue, rat kidney tissue, rat liver tissue, rat spleen tissue.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105 (Endoglin)
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene ENG
Gene Accession No. Q63961
Gene Alias AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Gene Symbols ENG
Host Species Rabbit
Immunogen E. coli-derived mouse CD105 recombinant protein (Position: E27-L226).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13805, 497010
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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