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Invitrogen™ CD105 (Endoglin) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579203

Catalog No. PIPA579203


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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: mouse lung tissue. IHC: mouse kidney tissue, mouse liver tissue, mouse spleen tissue, rat kidney tissue, rat liver tissue, rat spleen tissue.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD105 (Endoglin)
Polyclonal
Unconjugated
ENG
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Rabbit
Antigen Affinity Chromatography
RUO
13805, 497010
-20°C
Lyophilized
ELISA, Immunohistochemistry (Paraffin), Western Blot
500 μg/mL
PBS with 4mg trehalose and 0.05mg sodium azide
Q63961
ENG
E. coli-derived mouse CD105 recombinant protein (Position: E27-L226).
100 μg
Primary
Mouse, Rat
Antibody
IgG
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