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Invitrogen™ CD105 (Endoglin) Recombinant Rat Monoclonal Antibody (MJ7/18)
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Catalog No. PIMA548012
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200 μg
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Catalog No. Quantity
PIMA548012 200 μg
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Catalog No. PIMA548012 Supplier Invitrogen™ Supplier No. MA548012
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Description

Rat Recombinant Monoclonal Antibody

Specificity: MJ7/18 binds specifically to mouse CD105.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105 (Endoglin)
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone MJ7/18
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene ENG
Gene Accession No. Q63961
Gene Alias AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Gene Symbols ENG
Host Species Rat
Immunogen MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13805
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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