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Epredia™ Lab Vision™ CD105/Endoglin/TGF-β 1/3 Receptor Ab-3, Mouse Monoclonal Antibody

Catalog No. MS1290R1 Shop All Epredia Products
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MS1290R1 1 mL
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Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and flow cytometry applications.

CD105 or Endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2.

Host Species: Mouse

Clone: SN6h

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells.

Molecular Weight: 95 kDa (monomer) and 190kDa (dimer)

Positive Control: HUVEC cells, Tonsil, lymph node and thymus

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen CD105/Endoglin/TGF-beta1/3 Receptor Ab-3
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone SN6h
Conjugate Unconjugated
Formulation Ready-to-use for IHC (UVLP)
Host Species Mouse
Immunogen Purified GP160 from cell membrane glycoproteins of fresh non-T/non-B acute lymphoblastic leukemia cells
Quantity 1 mL
Regulatory Status RUO
Research Discipline Angiogenesis
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG2a κ
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