Invitrogen™ CD105 Monoclonal Antibody (MJ7/18)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA517943

Catalog No. PIMA517943

Description

MA5-17943 targets CD105/Endoglin in FACS, IHC, IP, and WB applications and shows reactivity with Mouse samples. The MA5-17943 immunogen is rat monoclonal antibody raised against inflamed mouse skin.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Specifications

• Antigen: CD105
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q63961
• Gene Symbols: ENG
• Immunogen: Rat monoclonal antibody raised against inflamed mouse skin.
• Quantity: 250 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: MJ7/18
• Conjugate: Unconjugated
• Gene: ENG
• Gene Alias: AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 13805
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid