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Invitrogen™ CD105 Monoclonal Antibody (MJ7/18), Biotin
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Catalog No. PIMA517944
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100 μg
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Catalog No. Quantity
PIMA517944 100 μg
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Catalog No. PIMA517944 Supplier Invitrogen™ Supplier No. MA517944
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Description

Rat Monoclonal Antibody

MA5-17944 targets CD105/Endoglin in FACS, IHC, IP, and WB applications and shows reactivity with Mouse samples. The MA5-17944 immunogen is rat monoclonal antibody raised against inflamed mouse skin.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone MJ7/18
Concentration 0.1 mg/mL
Conjugate Biotin
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene ENG
Gene Accession No. Q63961
Gene Alias AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Gene Symbols ENG
Host Species Rat
Immunogen Rat monoclonal antibody raised against inflamed mouse skin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13805
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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