Invitrogen™ CD105 Recombinant Rabbit Monoclonal Antibody (103), PerCP

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA546641

Catalog No. PIMA546641

Description

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human CD105 (Endoglin) (Met1-Gly586) and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Specifications

• Antigen: CD105
• Classification: Recombinant Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: P17813
• Gene Symbols: ENG
• Immunogen: Recombinant protein ecoding Human CD105 (Met1-Gly586).
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 103
• Conjugate: PerCP
• Gene: ENG
• Gene Alias: AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2022
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid