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Invitrogen™ CD106 (VCAM-1) Monoclonal Antibody (STA), PE-Cyanine7, eBioscience™

Mouse Monoclonal Antibody

$140.00 - $414.00

Specifications

Antigen CD106 (VCAM-1)
Clone STA
Concentration 5 μL/Test
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Applications Flow Cytometry
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
25-106-941
Encompass_Preferred
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Invitrogen™
25106941
25 Tests
Each for $140.00
Only null left
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50-112-3322
Encompass_Preferred
View Documents
Invitrogen™
25106942
100 Tests
Each for $414.00
Only null left
Add to Cart
 
Description

Description

Description: The STA monoclonal antibody reacts with human CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to Integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin alpha4beta7 (LPAM-1). Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response. Applications Reported: This STA antibody has been reported for use in flow cytometric analysis. Applications Tested: This STA antibody has been pre-titrated and tested by flow cytometric analysis of stimulated HUVEC. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product # 00-822-49) (100 μL of cell sample + 100 μL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product # 00-5333-54) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation...

VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.
Specifications

Specifications

CD106 (VCAM-1)
5 μL/Test
Flow Cytometry
PE-Cyanine7
Mouse
RUO
PBS with BSA and 0.09% sodium azide; pH 7.2
P19320
7412
Primary
Affinity Chromatography
STA
4°C, store in dark, DO NOT FREEZE!
Monoclonal
Liquid
IgG1 κ
Human
VCAM1
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B
VCAM1
Antibody
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