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CD107A Mouse anti-Human, Brilliant Violet 421, Clone: H4A3, BD

Catalog No. BDB566261 Shop All BD Biosciences Products
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BDB566261 25 Tests
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Catalog No. BDB566261 Supplier BD Biosciences Supplier No. 566261
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Description

Mouse Monoclonal Antibody

The H4A3 monoclonal antibody specifically binds to the heavily glycosylated 110 kDa Lysosomal-associated membrane protein 1, LAMP-1. LAMP-1 is a widely expressed intracellular antigen. It is also expressed on the surface of activated platelets, PHA-activated lymphocytes, cytotoxic T cells and NK cells, and some tumor cell lines, including U937 and KG1a. LAMP-1 has been shown to be a ligand for E-selectin-mediated cell adhesion. LAMP-1 and LAMP-2 (CD107b) are carriers for poly-N-acetyllactosamines and are able to display sialyl Le[x] termini.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD107A
Classification Monoclonal
Clone H4A3
Conjugate Brilliant Violet 421
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Gene Alias LAMP1, LAMP-1, LAMPA, LGP120
Host Species Mouse
Immunogen Human Adult Adherent Peripheral Blood Cells
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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