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CD114 Mouse, anti-Human, R718, Clone: LMM741, BD OptiBuild™

Catalog No. BDB751916 Shop All BD Biosciences Products
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BDB751916 50 μg
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Catalog No. BDB751916 Supplier BD Biosciences Supplier No. 751916
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Description

Mouse Monoclonal Antibody

The LMM741 monoclonal antibody specifically recognizes CD114 which is also known as the Granulocyte-Colony Stimulating Factor Receptor (G-CSFR). CD114 is a ∼150 kDa type I transmembrane glycoprotein that is encoded by CSF3R (colony stimulating factor 3 receptor) and belongs to the class 1 cytokine receptor family. CD114 is expressed on granulocytes, monocytes, dendritic cells, endothelial cells, platelets, placenta and myeloid leukemias and a variety of tumor cell lines. CD114 serves as the receptor for granulocyte colony stimulating factor (G-CSF) which plays a role in myeloid cell proliferation and differentiation. The immunogen used to generate this hybridoma was cells transfected with an expression vector containing a full-length cDNA encoding the human G-CSFR.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD114
Applications Flow Cytometry
Classification Monoclonal
Clone LMM741
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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