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CD117 Mouse anti-Human, PE, Clone: YB5.B8, BD

Catalog No. BDB555714 Shop All BD Biosciences Products
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0.1 mg
25 μg
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BDB555714 0.1 mg
BDB561682 25 μg
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Catalog No. BDB555714 Supplier BD Biosciences Supplier No. 555714
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Description

Mouse Monoclonal Antibody

The YB5.B8 monoclonal antibody specifically binds to CD117. CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes. CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD117
Applications Flow Cytometry
Classification Monoclonal
Clone YB5.B8
Concentration 0.2mg/mL
Conjugate PE
Description KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Acute myelocytic leukemia blasts
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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