Invitrogen™ CD119 (IFN gamma Receptor 1) Monoclonal Antibody (GIR-208 (GIR 208)), PE, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 12119941

Catalog No. 12-119-941

Description

Description: The monoclonal antibody reacts with human CD119 also known as the IFN gamma receptor 1 (alpha chain). IFN gamma R1 is found in a complex with IFN gamma receptor beta and recognizes with high affinity IFN gamma. Expression is ubiquitous but low, although some cell types, such as monocytes express higher levels. The GIR-208 monoclonal antibody is blocked from binding when IFN gamma is bound to the receptor. Applications Reported: This GIR-208 (GIR 208) antibody has been reported for use in flow cytometric analysis. Applications Tested: This GIR-208 (GIR 208) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Specifications

• Antigen: CD119 (IFN gamma Receptor 1)
• Classification: Monoclonal
• Concentration: 5 μL/Test
• Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
• Gene Accession No.: P15260
• Gene Symbols: IFNGR1
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3459
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: GIR-208 (GIR 208)
• Conjugate: PE
• Gene: IFNGR1
• Gene Alias: antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar
• Host Species: Mouse
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

For Research Use Only.