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Invitrogen™ CD119 (IFN gamma Receptor 1) Monoclonal Antibody (GR-20), Functional Grade, eBioscience™

Rat Monoclonal Antibody

$520.00

Specifications

Antigen CD119 (IFN gamma Receptor 1)
Clone GR-20
Concentration 1 mg/mL
Content And Storage 4°C
Applications Flow Cytometry, Functional Assay, Neutralization
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-112-2946
Encompass_Preferred
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Invitrogen™
16119385
500 μg
Each of 1 for $520.00
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Description

Description

Description: The monoclonal antibody GR-20 recognizes mouse CD119 also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense and expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types. The GR-20 antibody has been reported to block IFN gamma binding to CD119. Applications Reported: This GR-20 antibody has been reported for use in flow cytometric analysis and functional assays (blocking cytokine binding to the receptor). Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Specifications

Specifications

CD119 (IFN gamma Receptor 1)
1 mg/mL
Flow Cytometry, Functional Assay, Neutralization
Functional Grade
Rat
RUO
PBS with no preservative; pH 7.2
P15261
15979
Primary
Affinity chromatography
GR-20
4°C
Monoclonal
Liquid
IgG2a κ
Mouse
IFNGR1
antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; Ifgr; IFN-gamma receptor 1; IFN-gammaR; IFN-gamma-R1; IFN-gamma-R-alpha; Ifngr; IFNGR1; IMD27A; IMD27B; immune interferon receptor 1; INF-g receptor; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor 1; interferon-gamma receptor alpha chain; Nktar
IFNGR1
Antibody
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