CD11b Antibody (OX-42), HRP, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10065284H

Catalog No. NB000979

Description

CD11b Monoclonal specifically detects CD11b in Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry-Frozen.

Specifications

• Antigen: CD11b
• Classification: Monoclonal
• Conjugate: HRP
• Formulation: PBS with No Preservative
• Gene Symbols: ITGAM
• Immunogen: Mouse Monoclonal CD11b Antibody (OX-42) was made from rat peritoneal macrophages.
• Purification Method: Protein G purified
• Research Discipline: Breast Cancer, Cancer, Cellular Markers, Cytoskeleton Markers, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Microglia Markers, Myeloid Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers
• Gene ID (Entrez): 3684
• Target Species: Rat
• Isotype: IgG2a

• Applications: Immunohistochemistry, Immunohistochemistry (Frozen)
• Clone: OX-42
• Dilution: Immunohistochemistry, Immunohistochemistry-Frozen
• Gene Alias: antigen CD11b (p170), CD11 antigen-like family member B, CD11b, CD11b antigen, Cell surface glycoprotein MAC-1 subunit alpha, Complement component 3 receptor 3 subunit, CR-3 alpha chain, CR3A, CR3AMGC117044, integrin alpha-M, integrin, alpha M (complement component 3 receptor 3 subunit), Leukocyte adhesion receptor MO1, MAC-1, MAC1A, macrophage antigen alpha polypeptide, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6
• Host Species: Mouse
• Molecular Weight of Antigen: 127.9 kDa
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: NB100-65284 recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. This CD11b antibody also labels dendritic cells, granulocytes and microglial cells in the brain. Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Functionally, clone OX-42 inhibits complement mediated rosettes.
• Content And Storage: Store at 4°C in the dark.